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Pediatrics. 2020 Sep;146(3):e20200265. doi: 10.1542/peds.2020-0265. PMID: 32778539.In brief: This cross-sectional analysis of a nationally representative US sample showed that 25.5% of US children and adolescents (10.6 million in 2016) are eligible for screening for diabetes according to American Diabetes Association (ADA) criteria. The eligibility criteria showed l...

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ey0016.13-15 | Growth and Nutrition | ESPEYB16

13.15. The obesity transition: stages of the global epidemic

LM Jaacks , S Vandevijvere , A Pan , CJ McGowan , C Wallace , F Imamura , D Mozaffarian , B Swinburn , M Ezzati

Lancet Diabetes Endocrinol 2019; 7: 23140. DOI: 10.1016/S2213-587(19)30026-9 This study uses quantitative data from reputable global data sets to demonstrate that the epidemiology of obesity can be framed as a conceptual model of obesity transition. A new framework to classify the obesity epidemic is proposed that may assist policy makers and r...

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ey0019.5-1 | Novel treatments for rare skeletal disorders | ESPEYB19

5.1. Targeting TGF-β for treatment of osteogenesis imperfecta

IW Song , SC Nagamani , D Nguyen , I Grafe , VR Sutton , FH Gannon , E Munivez , MM Jiang , A Tran , M Wallace , P Esposito , S Musaad , E Strudthoff , S McGuire , M Thornton , V Shenava , S Rosenfeld , S Huang , R Shypailo , E Orwoll , B Lee

J Clin Invest. 2022 Apr 1;132(7):e152571. doi: 10.1172/JCI152571.Abstract: https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/35113812/In brief: Currently, there is no disease-specific therapy for osteogenesis imperfecta (OI) where most children, of all forms of OI, with significant fracture history, are managed by bisphosphonates...

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ey0020.7-4 | Gonadal Function and Fertility Issues in Childhood Cancer Survivors | ESPEYB20

7.4. Reduced-intensity conditioning mitigates risk for primary ovarian insufficiency but does not decrease risk for infertility in pediatric and young adult survivors of hematopoietic stem cell transplantation

JD Bender , H Oquendo-Del Toro , J Benoit , JC Howell , P Badia , SM Davies , MS Grimley , S Jodele , C Phillips , K Burns , R Marsh , A Nelson , G Wallace , CE Dandoy , A Pate , AC Strine , O Frias , L Breech , SR Rose , H Hoefgen , P Khandelwal , KC Myers

Brief summary: This single-center, retrospective, cross-sectional study compared the prevalence of gonadal insufficiency and infertility among 58 pubertal, post pubertal and young adult survivors of hematopoietic stem cell Transplantation (HSCT), treated with conditioning regimens of different intensity.Gonadal insufficiency or infertility affects almost all HSCT survivors who received a myeloablative conditioning (MAC) regimen. In recent years, reduced-...

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ey0020.7-14 | Long-Term Surveillance for Endocrine Complications in Childhood Cancer Survivors | ESPEYB20

7.14. Hypothalamic-pituitary and other endocrine surveillance among childhood cancer survivors

L van Iersel , RL Mulder , C Denzer , LE Cohen , HA Spoudeas , LR Meacham , E Sugden , AYN Schouten-van Meeteren , EW Hoving , RJ Packer , GT Armstrong , S Mostoufi-Moab , AM Stades , D van Vuurden , GO Janssens , C Thomas-Teinturier , RD Murray , N Di Iorgi , SJCMM Neggers , J Thompson , AA Toogood , H Gleeson , C Follin , E Bardi , L Torno , B Patterson , V Morsellino , G Sommer , SC Clement , D Srivastava , CE Kiserud , A Fernandez , K Scheinemann , S Raman , KCJ Yuen , WH Wallace , LS Constine , R Skinner , MM Hudson , LCM Kremer , W Chemaitilly , HM van Santen

Brief summary: In this extensive and updated review, the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) report expert consensus-based guidelines that harmonize recommendations for surveillance of endocrine disorders in childhood cancer survivors.This interdisciplinary panel of 42 international experts formulated new surveillance recommendations for hypothalamicpituitary (HP) dysfunction. Existing IGHG surveillan...

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ESPE Yearbook of Paediatric Endocrinology

12.1. Screening and diagnosis of prediabetes and diabetes in US children and adolescents

13.15. The obesity transition: stages of the global epidemic

5.1. Targeting TGF-β for treatment of osteogenesis imperfecta

7.4. Reduced-intensity conditioning mitigates risk for primary ovarian insufficiency but does not decrease risk for infertility in pediatric and young adult survivors of hematopoietic stem cell transplantation

7.14. Hypothalamic-pituitary and other endocrine surveillance among childhood cancer survivors

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